Mass treatment with statins

Pre-Treatment with Statins for Coronary Intervention: Pleiotropy of Statins or Effect of LDL-cholesterol Reduction?

Statins inhibit hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMCoAR), consequently suppressing cholesterol biosynthesis. Animal studies, epidemiologic studies, and clinical trials all support the low-density lipoprotein (LDL) hypothesis. The benefit of these statin drugs has greatly impacted treatment of cardiovascular diseases in primary and secondary prevention. Data from the resu...

statins in the treatment of hepatitis c

Treatment with statins and testosterone levels in men.

INTRODUCTION Statins belong to the most commonly used medicines worldwide. They affect cholesterol synthesis and thus they may suppress steroidogenesis. Our aim was to evaluate whether the use of statins is associated with the concentration of sex hormones.Material and methods/Results: In a population sample of men (n = 237) we found that subjects receiving statins had significantly lower conce...

modern surgical techniques in treatment of patients with cleft lip & cleft palate

چکیده ندارد.

Should treatment of sepsis include statins?

During the past decade, HMG-CoA reductase inhibitors (statins) have been shown to improve survival in patients with cardiovascular disease. Initially, the beneficial effects of statins were attributed simply to lipid reduction1; however, more recent data suggest that “pleiotropic” properties such as improvement of endothelial dysfunction, increased nitric oxide bioavailability, and antioxidativ...